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In preclinical models, Dihexa demonstrated superior pharmacokinetic properties, including good oral activity and effective BBB penetration, along with enhanced metabolic stability with a half-life of 335.5 minutes

Svizenska et al., 2008)

While each of these techniques has its advantages and drawbacks, all are burdened with the requirement that each instance of application be tailored to a particular protein or class of proteins with common binding properties or structure